An IDEAL Phase 2a, Single-arm, Single-center, Prospective Study of Two-step Radical Prostatectomy in the Treatment of Low- to Intermediate-risk Prostate Cancer Concomitant With Severe Benign Prostatic Hyperplasia
The goal of this observational study is to learn about the safety and efficacy of two-step radical prostatectomy in the treatment of low- to intermediate-risk prostate cancer patient with enlarged prostate and severe benign prostatic hyperplasia. The main question it aims to answer are: 1. Whether two-step prostatectomy is safe enough to decrease the surgical difficulty of these patients? 2. Whether the oncologic control is promising?
• Diagnosed as prostate cancer pathologically by prostate biopsy
• Evaluated as localized prostate cancer by imaging studies
• Prostate volume\>70mL evaluated by transrectal ultrasonography or multi-parametric magnetic resonance imaging
• Gleason score≤ 4+3=7
• Preoperative PSA\<20ng/mL
• Estimated survival\> 10 years；
• Informed consent is obtained from the patient